There are only certain security holes you can check for with any program. You can check your PHP configuration, Apache configuration, passwords, common bugs, etc. but you can't really check programatically for logic errors which might cause security holes.
Your best bet would be to do a thorough code review of the website. Or, better yet, have several other people do a thorough code review of the website, looking for security holes.
与恶龙缠斗过久,自身亦成为恶龙;凝视深渊过久,深渊将回以凝视…