I have two GKE clusters running in two different regions. Anthos Service Mesh is configured in each region for inter API communication. Question is should I configure Google Global Load Balancer to send the traffic or should I configure Istio Ingress gateway/Anthos Ingress gateway.
Yes, According to the GCP doc you can configure External HTTP(S) LB for Multi-region cluster. For more information please follow the documentation.
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