The issue with your request is specifically the "Supporting screen-readers", as by definition screen readers are a "bot" of some sort. If a screen-reader needs to be able to interpret the email address, then a page-crawler would be able to interpret it as well.
Also, the point of the mailto
attribute is to be the standard of how to do email addresses on the web. Asking if there is a second way to do that is sort of asking if there is a second standard.
Doing it through scripts will still have the same issue as once the page is loaded, the script would have been run and the email address rendered in the DOM (unless you populate the email address on click
or something). Either way, screen readers will still have issues with this since it's not already loaded.
Honestly, just get an email service with a half decent spam filter and specify a default subject line that is easy for you to sort in your inbox.
<a href="mailto:no-one@no-where.com?subject=Something to filter on">Email me</a>
What you're asking for is if the standard has two ways to do something, one for bots and the other for non-bots. The answer is it doesn't, and you have to just fight the bots as best you can.
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